[CD94/NKG2A--a kind of inhibitory receptor belonging to C-type lectin superfamily]

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2002 Dec;24(6):653-5.
[Article in Chinese]

Abstract

CD94/NKG2A is a kind of inhibitory receptor belonging to C-type lectin superfamily. It specifically expresses on the surface of some lymphocytes such as NK cells and T cells, and mediates inhibitory signal. In this mini-review, the structure of CD94/NKG2A molecule is described and its biological significance is discussed.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Antigens, CD / immunology*
  • HLA Antigens / immunology
  • HLA-E Antigens
  • Histocompatibility Antigens Class I / immunology
  • Humans
  • Killer Cells, Natural / immunology*
  • Lectins, C-Type / immunology*
  • NK Cell Lectin-Like Receptor Subfamily C
  • NK Cell Lectin-Like Receptor Subfamily D
  • Receptors, Immunologic / immunology*
  • Receptors, Natural Killer Cell
  • T-Lymphocytes / immunology

Substances

  • Antigens, CD
  • HLA Antigens
  • Histocompatibility Antigens Class I
  • KLRC1 protein, human
  • KLRD1 protein, human
  • Lectins, C-Type
  • NK Cell Lectin-Like Receptor Subfamily C
  • NK Cell Lectin-Like Receptor Subfamily D
  • Receptors, Immunologic
  • Receptors, Natural Killer Cell