[Effect of para-aminobenzonic acid on cell-surface hydrophobicity of Actinomyces viscosus]

Sichuan Da Xue Xue Bao Yi Xue Ban. 2003 Jul;34(3):491-3.
[Article in Chinese]

Abstract

Objective: To study the effect of Para-aminobenzonic acid (PABA) on cell-surface hydrophobicity of Actinomyces viscosus.

Methods: Microbial adhesion to hydrocarbons (MATH) was used to measure the cell-surface hydrophobicity of Actinomyces viscosus which grew in modified Carlsson medium with different dilution of PABA.

Results: Following the increase of concentration of PABA, the value of cell-surface hydrophobicity of Actinomyces viscosus decreased, which were 0.38900 +/- 0.00026, 0.25462 +/- 0.00168, 0.16360 +/- 0.00026 respectively(P < 0.05).

Conclusion: PABA could inhibit the adherence of Actinomyces viscosus by way of changing its cell-surface hydrophobicity.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • 4-Aminobenzoic Acid / pharmacology*
  • Actinomyces viscosus / drug effects*
  • Actinomyces viscosus / physiology
  • Bacterial Adhesion / drug effects*
  • Humans
  • Hydrophobic and Hydrophilic Interactions

Substances

  • 4-Aminobenzoic Acid