Sixty cases of pregnancy with thrombocytopenia were analyzed. Bleeding syndrome was found in 36 patients during pregnancy, with 7 cases suffering from massive hemorrhage during delivery and a postpartum hemorrhage rate of 11.7%. There was a negative correlation between the platelet level and the amount of bleeding during gestation and delivery. We suggest that cortico steroid is necessary with a platelet count less than 50 x 10(9)/L in the middle or late trimester of pregnancy to reduce the bleeding tendency during delivery, as well as the incidence of thrombocytopenia in the newborn infant use of excessive platelet transfusion is not encouraged, since it implicates an increase in antibody-induction (PAIG) and probability of C type hepatitis in the recipient. Platelet transfusion should be reserved only for the treatment of serious hemorrhage. There were 53 newborn infants, 7 of whom (13.2%) suffered from thrombocytopenia, with a mortality of 1.9% (7/53) during the perinatal.