Cigarette smoking continues to be a national healthcare crisis and is responsible for unacceptable levels of suffering, disease, and death. The barriers to effective intervention such as training, time, and reimbursement are formidable, although the situation is improving as the proper behavioral approaches and medications become clearly defined. Application of these practical points is an acquired skill that takes time. Incorporating these suggestions into daily practice ensures that your smoking patients have the best opportunity to quit and the highest level of care.