[Botulinum toxin and spinal cord injury]

Ann Readapt Med Phys. 2003 Jul;46(6):296-8. doi: 10.1016/s0168-6054(03)00101-6.
[Article in French]

Abstract

Objective: To realize a clarification about the interest of the use of botulinum toxin in spinal cord injured patients.

Method: Interrogation of Medline database (crossing of botulinum toxin and spinal cord injury). We have also analyzed data from R. Poincaré Hospital in 2001.

Results: Three articles of the twenty-five selected, treated effectively of botulinum toxin effect in the limbs muscles of spinal cord injured patients.

Discussion: There are some indications of botulinum toxin in spinal cord injured patients ASIA C and D when spasticity induce focal functional discomfort. Indications are exceptional for ASIA A and B patients. No study showed improvement of functional abilities after botulinum toxin injection in spinal cord injured patients. Published studies only covered small number of patients.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Anti-Dyskinesia Agents / administration & dosage
  • Anti-Dyskinesia Agents / pharmacology*
  • Botulinum Toxins / administration & dosage
  • Botulinum Toxins / pharmacology*
  • Clinical Trials as Topic
  • Humans
  • Muscle Spasticity / drug therapy*
  • Muscle Spasticity / etiology
  • Spinal Cord Injuries / drug therapy*
  • Treatment Outcome

Substances

  • Anti-Dyskinesia Agents
  • Botulinum Toxins