Parathyroid carcinoma: difficult management options

Indian J Cancer. 2002 Jul-Sep;39(3):119-22.

Abstract

Parathyroid carcinoma is a rare cause of primary hyperparathyroidism and these tumours are usually hyperfunctional as opposed to other malignant endocrine tumors. Surgery is the only effective treatment while nonsurgical modalities yield poor results. We report a patient, who presented with palpable mass in the neck and severe hypercalcemia. He underwent debulking surgery and received allendronate, calcitonin, dacarbazine followed by in- situ alcohol instillation with some success.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Alcohols / therapeutic use
  • Alendronate / therapeutic use
  • Antineoplastic Agents, Alkylating / therapeutic use*
  • Calcitonin / therapeutic use
  • Combined Modality Therapy
  • Dacarbazine / therapeutic use*
  • Humans
  • Hypercalcemia / drug therapy
  • Hypercalcemia / etiology*
  • Male
  • Parathyroid Neoplasms / complications
  • Parathyroid Neoplasms / drug therapy*
  • Parathyroid Neoplasms / surgery

Substances

  • Alcohols
  • Antineoplastic Agents, Alkylating
  • Dacarbazine
  • Calcitonin
  • Alendronate