Abstract
A novel class of DNA cleavage agents are reported that derive activity from amino acids tethered to a photoactive intercalator.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acids / chemistry
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Amino Acids / pharmacology*
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Benzothiazoles
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DNA / chemistry
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DNA / drug effects*
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DNA / radiation effects
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Electrophoresis, Agar Gel
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Escherichia coli / genetics
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Fluorescent Dyes / chemistry
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Molecular Structure
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Photosensitizing Agents / chemistry
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Photosensitizing Agents / pharmacology*
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Plasmids / chemistry
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Plasmids / drug effects
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Plasmids / radiation effects
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Quinolines
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Thiazoles / chemistry
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Time Factors
Substances
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Amino Acids
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Benzothiazoles
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Fluorescent Dyes
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Photosensitizing Agents
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Quinolines
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Thiazoles
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thiazole orange
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DNA