Respiratory health and air pollution: additive mixed model analyses

Biostatistics. 2001 Sep;2(3):337-49. doi: 10.1093/biostatistics/2.3.337.

Abstract

We conduct a reanalysis of data from the Utah Valley respiratory health/air pollution study of Pope and co-workers (Pope et al., 1991) using additive mixed models. A relatively recent statistical development (e.g. Wang, 1998; Verbyla et al., 1999; Lin and Zhang, 1999), the methods allow for smooth functional relationships, subject-specific effects and time series error structure. All three of these are apparent in the Utah Valley data.