Among 66 consecutive adult heart transplant recipients operated on from January 1988 to October 1991, 11 experimented early graft dysfunction (4 of them died). Mean donor's age was 37.4 +/- 11 years; 9 patients were older than 50 years; 85 percent of donors received dopamine. Were found without any significant influence on early graft function: donor's age, weight mismatch, duration of donor's intensive care, dose of dopamine administered, external cardiac massage and relative hemodynamic instability, and ischemic time. Conversely, a history of chronic alcoholism in the donor is of pejorative significance, which is not without consequences in view of the current scarcity of donors.