Clofarabine-induced acral erythema during the treatment of patients with myelodysplasia and acute leukemia: report of two cases

Leuk Lymphoma. 2003 Aug;44(8):1405-7. doi: 10.1080/1042819031000090183.

Abstract

Acral erythema has been associated with a number of chemotherapeutic agents, but there are no reports of clofarabine-induced acral erythema in the literature. We describe two patients who developed acral erythema after receiving clofarabine. One patient had myelodysplastic syndrome while the other had acute lymphoblastic leukemia.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenine Nucleotides
  • Adolescent
  • Arabinonucleosides / adverse effects*
  • Arabinonucleosides / therapeutic use
  • Clofarabine
  • Dose-Response Relationship, Drug
  • Erythema / chemically induced*
  • Erythema / pathology
  • Female
  • Foot Dermatoses / chemically induced
  • Foot Dermatoses / pathology
  • Hand Dermatoses / chemically induced
  • Hand Dermatoses / pathology
  • Humans
  • Middle Aged
  • Myelodysplastic Syndromes / complications*
  • Myelodysplastic Syndromes / drug therapy
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy

Substances

  • Adenine Nucleotides
  • Arabinonucleosides
  • Clofarabine