Objective: To report a case of IVF with apparently normal female and male gametes that resulted in the development of only multipronuclear oocytes (instead of oocytes containing two pronuclei) and was successfully treated with ICSI.
Design: Case report.
Setting: A university hospital.
Patient(s): A 35-year-old woman with unexplained infertility and her partner, a 38-year-old man with normozoospermia.
Intervention(s): Intracytoplasmic sperm injection.
Main outcome measure(s): Oocyte fertilization and pregnancy.
Result(s): Normal fertilization and an ongoing pregnancy occurred after transfer of two embryos.
Conclusion(s): Although the usual indication for ICSI is male subfertility, it can also be used to successfully treat oocyte defects.