Effects of the MEK inhibitor CI-1040 (PD 184352) on progenitor growth from normal and myelodysplastic marrow

Haematologica. 2003 Sep;88(9):1072-4.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Benzamides / pharmacology*
  • Bone Marrow / drug effects*
  • Bone Marrow / enzymology
  • Bone Marrow / pathology
  • Bone Marrow / physiology
  • HL-60 Cells
  • Hematopoietic Stem Cells / drug effects*
  • Hematopoietic Stem Cells / enzymology
  • Hematopoietic Stem Cells / pathology
  • Hematopoietic Stem Cells / physiology
  • Humans
  • Mitogen-Activated Protein Kinase Kinases / antagonists & inhibitors*
  • Myelodysplastic Syndromes / enzymology
  • Myelodysplastic Syndromes / metabolism*
  • Myelodysplastic Syndromes / pathology
  • Tumor Cells, Cultured

Substances

  • 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
  • Benzamides
  • Mitogen-Activated Protein Kinase Kinases