Sequencing and chromosomal localization of Fabp6 and an intronless Fabp6 segment in the rat

Anita Bonné; Claudia Gösele; Maria den Bieman; Gert Gillissen; Thomas Kreitler; Michal Pravenec; Vladimir Kren; Hein van Lith; Bert van Zutphen

doi:10.1023/a:1024968606162

Sequencing and chromosomal localization of Fabp6 and an intronless Fabp6 segment in the rat

Mol Biol Rep. 2003 Sep;30(3):173-6. doi: 10.1023/a:1024968606162.

Authors

Anita Bonné¹, Claudia Gösele, Maria den Bieman, Gert Gillissen, Thomas Kreitler, Michal Pravenec, Vladimir Kren, Hein van Lith, Bert van Zutphen

Affiliation

¹ Department of Laboratory Animal Science, Faculty of Veterinary Science, Utrecht University, P.O. Box 80166, 3508 TD Utrecht, The Netherlands. [email protected]

PMID: 12974472
DOI: 10.1023/a:1024968606162

Abstract

The fatty acid binding protein 6 gene (Fabp6) codes for ileal lipid binding protein. After sequencing of rat Fabp6, the gene was localized in a radiation hybrid (RH) map on chromosome 10. An intronless Fabp6 segment was found in four related rat inbred strains (SHR; SHRSP; WKY; and OKA), but not in 62 other rat inbred strains. The intronless Fabp6 segment, which might be a pseudogene of Fabp6, was localized on rat chromosome 15.

MeSH terms

Animals
Base Sequence
Carrier Proteins / genetics*
Chromosome Mapping
Chromosomes, Mammalian / genetics*
Cloning, Molecular
Exons / genetics
Fatty Acid-Binding Proteins
Gastrointestinal Hormones
Introns / genetics*
Molecular Sequence Data
Pseudogenes / genetics
Rats
Rats, Inbred Strains
Sequence Analysis, DNA

Substances

Carrier Proteins
Fatty Acid-Binding Proteins
Gastrointestinal Hormones
fatty acid-binding protein 6