Fibrous dysplasia with locally aggressive malignant change

Arch Orthop Trauma Surg. 1992;111(3):183-6. doi: 10.1007/BF00388097.

Abstract

This is a case report of a tumour which showed all the histological features of fibrous dysplasia without any features of high-grade malignancy, yet had become locally aggressive, causing cortical erosion and extension into soft tissue. Fibrous dysplasia is a well-recognised entity that encompasses monostotic lesions, polyostotic involvement and Albright's syndrome [6, 8]. Lesions in bone usually spare the epiphysis before puberty, but often involve the epiphyseal area after maturity and can progress during adult life [3]. Unless cystic [6, 10] or malignant change [7, 10, 11] occurs, fibrous dysplasia usually remains contained within bone.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bone Neoplasms / diagnostic imaging
  • Bone Neoplasms / pathology*
  • Bone Neoplasms / surgery
  • Diagnosis, Differential
  • Female
  • Fibrous Dysplasia of Bone / diagnostic imaging
  • Fibrous Dysplasia of Bone / pathology*
  • Fibrous Dysplasia of Bone / surgery
  • Histiocytoma, Benign Fibrous / pathology
  • Humans
  • Mesenchymoma / pathology
  • Osteosarcoma / pathology
  • Radiography
  • Shoulder Joint / diagnostic imaging
  • Shoulder Joint / pathology*
  • Shoulder Joint / surgery
  • Soft Tissue Neoplasms / diagnostic imaging
  • Soft Tissue Neoplasms / pathology*
  • Soft Tissue Neoplasms / surgery