Abstract
The results of the clinico-morphological studies carried out in 30 patients with the anterior-horn variety of amyotrophic lateral sclerosis (ALS) (CNS morphology was investigated in 6 cases) demonstrate this variety to be characterized by early fading of the tendinous periosteal reflexes, rapid development of amyotrophies, weak intensity of pyramid system lesions. This is supported by morphological studies of the CNS and allows advancing an opinion in favour of the priority of motoneuronal injury.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Adult
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Aged
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Amyotrophic Lateral Sclerosis / classification
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Amyotrophic Lateral Sclerosis / diagnosis*
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Amyotrophic Lateral Sclerosis / pathology
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Arm / innervation
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Brain / pathology*
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Diagnosis, Differential
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Female
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Humans
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Leg / innervation
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Male
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Middle Aged
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Motor Neurons / pathology*
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Motor Neurons / ultrastructure
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Muscular Atrophy / diagnosis
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Muscular Atrophy / pathology
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Myelin Sheath / ultrastructure
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Quadriplegia / diagnosis
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Quadriplegia / pathology
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Reflex, Abnormal / physiology
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Spinal Cord / pathology*