Hemimegalencephaly and normal intellectual development

J Neurol Neurosurg Psychiatry. 1992 Aug;55(8):720-2. doi: 10.1136/jnnp.55.8.720.

Abstract

Hemimegalencephaly is a rare congenital malformation characterised by overgrowth of one hemisphere. Although it is commonly thought to be associated with neurological deficits, developmental delay, and intractable epilepsy, the clinical expression of hemimegalencephaly, can vary widely. This patient was neurologically and neuropsychologically normal apart from rare partial seizures.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain / abnormalities*
  • Brain / physiopathology
  • Cerebral Cortex / abnormalities
  • Cerebral Cortex / physiopathology
  • Dominance, Cerebral / physiology*
  • Epilepsy, Tonic-Clonic / physiopathology*
  • Humans
  • Intelligence / physiology*
  • Magnetic Resonance Imaging
  • Male
  • Neurologic Examination
  • Synaptic Transmission / physiology
  • Tomography, X-Ray Computed