Abstract
We report the cloning and the sequencing of a cDNA coding for the mature bovine interleukin 7 (IL-7). The clone was isolated from a bovine leukemia virus (BLV)-induced B cell-lymphosarcoma cDNA library. The 5' non-coding sequence and the sequence of the signal peptide were obtained from a clone isolated from a bovine genomic library. The entire bovine IL-7 protein is 176 amino acids long and shows 75 and 65% homology to published sequences of human and murine IL-7, respectively.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Base Sequence
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Cattle
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Cloning, Molecular
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DNA
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Enzootic Bovine Leukosis / genetics
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Humans
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Interleukin-7 / genetics*
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Leukemia Virus, Bovine / metabolism
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Molecular Sequence Data
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Protein Sorting Signals / genetics
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Sequence Homology, Amino Acid
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Sequence Homology, Nucleic Acid
Substances
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Interleukin-7
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Protein Sorting Signals
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DNA
Associated data
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GENBANK/S44931
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GENBANK/S44934
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GENBANK/X58544
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GENBANK/X60109
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GENBANK/X62255
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GENBANK/X62256
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GENBANK/X62257
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GENBANK/X62258
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GENBANK/X62259
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GENBANK/X64540