Abstract
The authors report on the case of a child with the nephrotic syndrome complicated by thrombosis of superior longitudinal sinus, bilateral massive pulmonary embolism resulting in a sudden death. A dramatic deficiency in factor XII was demonstrated; the pathophysiology and management of such an abnormality are discussed.
MeSH terms
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Child, Preschool
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Cyclophosphamide / therapeutic use
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Death, Sudden / etiology
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Factor XII Deficiency / etiology
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Humans
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Male
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Methylprednisolone / therapeutic use
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Nephrotic Syndrome / complications*
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Nephrotic Syndrome / diagnostic imaging
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Nephrotic Syndrome / drug therapy
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Pulmonary Embolism / diagnostic imaging
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Pulmonary Embolism / etiology*
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Radiography
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Sinus Thrombosis, Intracranial / diagnostic imaging
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Sinus Thrombosis, Intracranial / etiology*
Substances
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Cyclophosphamide
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Methylprednisolone