Alcohol injection: a treatment for ruptured hepatocellular carcinoma

Surg Oncol. 1992 Feb;1(1):61-3. doi: 10.1016/0960-7404(92)90057-r.

Abstract

Nine patients with bleeding from a ruptured hepatocellular carcinoma had absolute alcohol injection. Laparotomy and alcohol injection stopped the bleeding in seven patients. Injection under laparoscopic visualization was attempted in two patients and in one patient haemostatis was achieved initially. He rebled, however, 4 h later and laparotomy failed to control the bleeding. He died 2 days later because of coagulopathy and renal failure. In the second patient, bleeding was not controlled laparoscopically and immediate laparotomy and alcohol injection stopped the bleeding. The eight patients who survived left hospital between 8 and 21 days after surgery (median 10 days). In our experience, laparotomy and alcohol injection achieved good results in bleeding hepatocellular carcinoma.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Carcinoma, Hepatocellular / complications
  • Carcinoma, Hepatocellular / mortality
  • Carcinoma, Hepatocellular / therapy*
  • Combined Modality Therapy
  • Ethanol / administration & dosage*
  • Female
  • Hemoperitoneum / etiology
  • Hemoperitoneum / therapy
  • Hemostasis, Surgical / methods
  • Humans
  • Laparotomy
  • Liver Neoplasms / complications
  • Liver Neoplasms / mortality
  • Liver Neoplasms / therapy*
  • Male
  • Middle Aged
  • Rupture, Spontaneous

Substances

  • Ethanol