Abstract
We present an extremely serious clinical case of Stevens-Johnson syndrome, the evolution of which has been followed for 3 years. The etiology was unknown, although it was related with the administration of amoxicillin. We found a type III immunity mechanism involving immune complexes. The serious complications affected the skin, mucosae and internal organs. The present sequelae are: esophageal stenosis, pneumopathy with a 50% deficit of pulmonary perfusion and bilateral trichiasis.
MeSH terms
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Amoxicillin / adverse effects
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Antigen-Antibody Complex / metabolism
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Child, Preschool
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Complement System Proteins / metabolism
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Esophageal Stenosis / complications
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Eye Diseases / complications
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Eyelashes / pathology
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Female
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Humans
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Lung Diseases / complications
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Lung Diseases / physiopathology
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Stevens-Johnson Syndrome / complications*
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Stevens-Johnson Syndrome / etiology
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Stevens-Johnson Syndrome / immunology
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Ventilation-Perfusion Ratio
Substances
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Antigen-Antibody Complex
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Amoxicillin
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Complement System Proteins