Abstract
Vascular autonomic receptors in amphibians exhibit difference from more evolved mammalian species. Vascular perfusion studies in frog indicate constrictions by prominent muscarinic but rudimentary nicotinic constrictive regulation by cholinergic systems. Difference from classical effect-patterns of pharmacological interventions, observed in the study, make room to visualise complexity of additional regulatory mechanisms.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adrenergic alpha-Antagonists / pharmacology
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Animals
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Autonomic Nerve Block
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Autonomic Nervous System / drug effects*
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Blood Vessels / drug effects*
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Blood Vessels / innervation
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Choline / analogs & derivatives
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Choline / pharmacology*
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Cholinergic Fibers / drug effects
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Cholinergic Fibers / physiology
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Dose-Response Relationship, Drug
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Drug Interactions
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Esters / pharmacology
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Female
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Ganglia, Autonomic / drug effects
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Ganglia, Autonomic / physiology
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Male
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Models, Biological
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Muscarinic Antagonists
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Ranidae / physiology*
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Vasoconstrictor Agents / pharmacology*
Substances
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Adrenergic alpha-Antagonists
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Esters
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Muscarinic Antagonists
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Vasoconstrictor Agents
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Choline