[DNA markers linked to Huntington's disease (D4S10 and D4S95) in Spanish families: preliminary results]

Rev Clin Esp. 1992 Apr;190(6):299-301.
[Article in Spanish]

Abstract

We have studied six Spanish families with at least one affected member with Huntington's disease, using RFLPs from probes linked to the gene. Our results suggest a genetic homogeneity in our population and show a 100% of informativity with the probes and enzymes used.

Publication types

  • Comparative Study
  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • DNA / genetics*
  • Gene Frequency / genetics
  • Genetic Markers / genetics
  • Humans
  • Huntington Disease / genetics*
  • Pedigree
  • Polymorphism, Restriction Fragment Length
  • Spain

Substances

  • Genetic Markers
  • DNA