[Clinical assessment of a group of children with juvenile rheumatoid arthritis receiving long-term treatment with oral gold salt]

Minerva Pediatr. 1992 Dec;44(12):617-22.
[Article in Italian]

Abstract

The authors assess the efficacy of gold salt treatment for juvenile rheumatoid arthritis. The study was carried out on 16 children suffering from mono-pauciarticular, polyarticular and systemic arthritis. Treatment consisted of the administration of auranofin alone in a group of 8 children and auranofin associated to corticosteroids in a second group of 8 children. A marked improvement in clinical conditions was observed with slight transitory side effects at follow-up after 12 and 24 months.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Antirheumatic Agents / therapeutic use*
  • Arthritis, Juvenile / therapy*
  • Auranofin / adverse effects
  • Auranofin / pharmacokinetics
  • Child
  • Child, Preschool
  • Digestive System / drug effects
  • Evaluation Studies as Topic
  • Female
  • Follow-Up Studies
  • Gold Sodium Thiomalate / pharmacology
  • Gold Sodium Thiomalate / therapeutic use*
  • Humans
  • Male

Substances

  • Antirheumatic Agents
  • Gold Sodium Thiomalate
  • Auranofin