Caspofungin salvage therapy in a neutropenic patient with probable invasive aspergillosis: a case report

F S Taccone; R Marechal; N Meuleman; M Aoun

doi:10.1007/s00520-003-0522-0

Caspofungin salvage therapy in a neutropenic patient with probable invasive aspergillosis: a case report

Support Care Cancer. 2003 Nov;11(11):742-4. doi: 10.1007/s00520-003-0522-0. Epub 2003 Sep 6.

Authors

F S Taccone¹, R Marechal, N Meuleman, M Aoun

Affiliation

¹ Intensive Care Unit (ASTI), Institut Jules Bordet, Centre des Tumeurs de l'Université Libre de Bruxelles, Brussels, Belgium.

PMID: 13680323
DOI: 10.1007/s00520-003-0522-0

Abstract

A 47-year-old man with acute lymphocytic leukemia was admitted in intensive care unit (ICU) because of respiratory failure. He had febrile neutropenia and probable invasive pulmonary aspergillosis (IA). Amphotericin B renal toxicity and clinical deterioration prompted a shift to caspofungin and resulted in a successful response.

Publication types

Case Reports

MeSH terms

Antifungal Agents / administration & dosage*
Antineoplastic Agents / administration & dosage
Antineoplastic Agents / adverse effects*
Aspergillosis* / drug therapy
Aspergillosis* / immunology
Burkitt Lymphoma / drug therapy
Caspofungin
Echinocandins
Humans
Lipopeptides
Lung Diseases, Fungal* / drug therapy
Lung Diseases, Fungal* / immunology
Male
Middle Aged
Neutropenia / chemically induced
Neutropenia / complications*
Neutropenia / drug therapy
Peptides / administration & dosage*
Peptides, Cyclic*
Remission Induction
Salvage Therapy*
Time Factors
Treatment Outcome

Substances

Antifungal Agents
Antineoplastic Agents
Echinocandins
Lipopeptides
Peptides
Peptides, Cyclic
Caspofungin