Abstract
Fc gamma receptors are a group of three different receptors with several subtypes. They are widely distributed on many cells of the immune system and contribute to the pathogenesis of immune complex- and autoantibody-mediated diseases such as vasculitis, rheumatoid arthritis, idiopathic thrombocytopenic purpura or autoimmune neutropenia. This review focuses on the structure, distribution and function in Fc gamma receptors and their subtypes.
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Antigen-Antibody Complex / metabolism
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Antigens, CD / physiology
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Antigens, Differentiation / classification
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Antigens, Differentiation / physiology*
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Antigens, Differentiation / ultrastructure
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Autoimmune Diseases / immunology*
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Humans
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Ligands
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Phagocytosis
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Protein Conformation
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Receptors, Fc / classification
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Receptors, Fc / physiology*
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Receptors, Fc / ultrastructure
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Receptors, IgG
Substances
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Antigen-Antibody Complex
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Antigens, CD
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Antigens, Differentiation
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Ligands
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Receptors, Fc
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Receptors, IgG