Failure of vaccination against hepatitis B with Gen H-B-Vax-D in immunosuppressed heart transplant recipients

D Wagner; I Wagenbreth; R Stachan-Kunstyr; J Flik

doi:10.1007/BF00184798

Failure of vaccination against hepatitis B with Gen H-B-Vax-D in immunosuppressed heart transplant recipients

Clin Investig. 1992 Jul;70(7):585-7. doi: 10.1007/BF00184798.

Authors

D Wagner¹, I Wagenbreth, R Stachan-Kunstyr, J Flik

Affiliation

¹ Institut für Virologie und Seuchenhygiene, Medizinische Hochschule Hannover.

PMID: 1392427
DOI: 10.1007/BF00184798

Abstract

Some 86 heart transplant recipients under immunosuppressive therapy were vaccinated against hepatitis B using the vaccine Gen H-B-Vax-D, but 95.3% failed to develop protective levels of HBs-specific antibody (more than 10 U/l) after the third vaccination.

MeSH terms

Female
Heart Transplantation*
Hepatitis B / epidemiology
Hepatitis B / etiology*
Hepatitis B / prevention & control
Hepatitis B Vaccines*
Humans
Immunocompromised Host*
Immunosuppression Therapy / adverse effects
Male
Middle Aged
Postoperative Complications / epidemiology
Postoperative Complications / etiology*
Postoperative Complications / prevention & control
Transfusion Reaction*
Vaccination*

Substances

Hepatitis B Vaccines