Starfish saponins, 48. Isolation of fifteen sterol constituents (six glycosides and nine polyhydroxysteroids) from the starfish Solaster borealis

J Nat Prod. 1992 Jul;55(7):866-77. doi: 10.1021/np50085a005.

Abstract

This paper reports a complete steroid glycoside and polyhydroxysteroid analysis of the starfish Solaster borealis, collected at Mutsu Bay, Japan. The glycosides include a new pentaglycoside steroid sulfate ("asterosaponin"), designated solasteroside A [1], two new sulfated 24-O-diglycosides, both with the common 5 alpha-cholesta-3 beta,6 alpha,8,15 alpha, 24-pentaol aglycone, borealosides A [2] and B [3], two new 24-O-(3-O-methyl)xylosides, borealosides C [4] and D [5], having the same aglycone with an additional hydroxy group at 4 beta-position in 5, and the known amurensoside B, previously isolated from Asterias amurensis. Among the polyhydroxysteroid constituents, four (7-10) are new, and five (11-15) have previously been isolated from starfishes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromatography, High Pressure Liquid
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Hydroxysteroids / chemistry
  • Hydroxysteroids / isolation & purification*
  • Molecular Structure
  • Saponins / chemistry
  • Saponins / isolation & purification*
  • Starfish / chemistry*
  • Sterols / chemistry
  • Sterols / isolation & purification*

Substances

  • Glycosides
  • Hydroxysteroids
  • Saponins
  • Sterols