The anticoagulants protein C and protein S display potent antiinflammatory and immunosuppressive effects relevant to transplant biology and therapy

Transplant Proc. 1992 Oct;24(5):2302-3.

Authors

W W Hancock¹, A Tsuchida, H Hau, N M Thomson, H H Salem

Affiliation

¹ Department of Pathology and Immunology, Monash Medical School, Melbourne, Victoria, Australia.

PMID: 1413069

No abstract available

MeSH terms

Animals
Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
Cells, Cultured
Heart Transplantation / immunology
Heart Transplantation / physiology*
Humans
Immunosuppressive Agents / pharmacology*
Interleukin-1 / biosynthesis
Kidney Transplantation / immunology
Kidney Transplantation / physiology*
Monocytes / drug effects
Monocytes / immunology
Monocytes / physiology*
Protein C / pharmacology*
Protein S / pharmacology*
Rats
Rats, Inbred BN
Rats, Inbred Lew
Transplantation, Homologous
Tumor Necrosis Factor-alpha / biosynthesis

Substances

Anti-Inflammatory Agents, Non-Steroidal
Immunosuppressive Agents
Interleukin-1
Protein C
Protein S
Tumor Necrosis Factor-alpha