Abstract
The effect of global immunosuppression by sublethal whole body X-irradiation on the development of cerebral oedema was assessed 24 h after right middle cerebral artery occlusion in the rat. Irradiation produced a significant leukopenia and thrombocytopaenia, and significantly reduced cortical oedema when compared to non-irradiated control animals.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Blood Platelets / immunology*
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Blood Platelets / radiation effects
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Brain / immunology
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Brain / radiation effects
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Brain Edema / immunology*
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Cerebral Infarction / immunology*
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Immunosuppression Therapy*
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Leukocyte Count / radiation effects
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Male
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Neutrophils / immunology*
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Neutrophils / radiation effects
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Platelet Count / radiation effects
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Radiation Injuries, Experimental / immunology*
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Rats
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Rats, Wistar
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Specific Gravity
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Whole-Body Irradiation*