Abstract
Erythropoietin levels have been determined in 24 patients with different gynecologic malignancies, who were treated with cisplatinum and endoxan. A statistically highly significant decrease was demonstrated 2 h after starting treatment with a further significant decrease at 6 h. After 12 h the erythropoietin concentrations returned to values similar to those before treatment started.
MeSH terms
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Adult
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Aged
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Antineoplastic Combined Chemotherapy Protocols / adverse effects*
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Cisplatin / administration & dosage
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Cisplatin / adverse effects
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Cyclophosphamide / administration & dosage
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Cyclophosphamide / adverse effects
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Erythropoietin / blood*
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Female
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Genital Neoplasms, Female / blood
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Genital Neoplasms, Female / drug therapy*
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Humans
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Middle Aged
Substances
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Erythropoietin
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Cyclophosphamide
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Cisplatin