[Role of leukocyte adhesion in filterability of blood cell suspensions]

Biull Eksp Biol Med. 1992 May;113(5):488-9.
[Article in Russian]

Abstract

We investigated blood cells suspension filterability of 16 donors. The filtration was performed trough 5 microns-pore nuclear filters at constant perfusion pressure 10(5) din/cm2. We estimated also the adherence of leukocytes and platelets on nylon. The adherence of platelets and mononuclear leukocytes reduced the level of the suspension filterability only by 21% (p > 0.05). The presence of nonadhesive polynuclear leukocytes in the suspensions did not change practically their filterability. The addition in the suspensions of adhesive polynuclear leukocytes reduced suspension filterability dramatically.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Blood Cells*
  • Blood Donors
  • Filtration* / instrumentation
  • Humans
  • Leukocytes / physiology*
  • Leukocytes, Mononuclear / physiology
  • Neutrophils / physiology
  • Platelet Adhesiveness
  • Tissue Adhesions