Endometrioid carcinoma of the ovary and endometriosis: the association in postmenopausal women

Gynecol Oncol. 1992 Oct;47(1):71-5. doi: 10.1016/0090-8258(92)90079-x.

Abstract

Histologic material from 42 patients with endometrioid carcinomas of the ovary was reviewed. Ovarian endometriosis was present in 11 cases (26%) and 8 of these patients were postmenopausal. The exact site of transition from benign to malignant epithelium was observed in 4 cases. The clinical characteristics of patients with associated endometriosis were not significantly different from those without this finding except that endometriosis was present only in patients with Grade 1 or Grade 2 carcinomas. These data suggest that ovarian endometriosis in the postmenopausal patient has the potential to undergo malignant transformation and, when detected, should be removed surgically.

MeSH terms

  • Adenocarcinoma / complications*
  • Adenocarcinoma / epidemiology
  • Adenocarcinoma / pathology
  • Adult
  • Aged
  • Aged, 80 and over
  • Cell Transformation, Neoplastic / pathology
  • Endometriosis / complications*
  • Endometriosis / epidemiology
  • Endometriosis / pathology
  • Female
  • Humans
  • Menopause*
  • Middle Aged
  • Ovarian Neoplasms / complications*
  • Ovarian Neoplasms / epidemiology
  • Ovarian Neoplasms / pathology