PET-fluorodeoxyglucose of cranial and spinal neuromas

J Nucl Med. 1992 Nov;33(11):1931-4.

Abstract

Five patients with eighth nerve, one with ninth nerve and one with cervical neuromas were studied with PET and [18F] fluorodeoxyglucose (FDG). Four of the patients had had surgery prior to the PET study, and six patients had subsequent surgery. All tumors were well-visualized on the PET images. Only one patient with bilateral acoustic neuroma exhibited tumor recurrence or growth after the PET study; these two lesions showed the highest FDG uptakes in the PET studies (tumor-to-cerebellum ratio of 0.93-0.98). All other tumors were relatively hypometabolic (tumor-cerebellum ratios of 0.43-0.65) and showed no tumor growth or recurrence during follow-up periods ranging from 5 to 8 yr. These results suggest that PET-FDG may be of value in the evaluation of cranial and spinal schwannomas.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cranial Nerve Neoplasms / diagnostic imaging*
  • Deoxyglucose / analogs & derivatives*
  • Female
  • Fluorodeoxyglucose F18
  • Humans
  • Male
  • Middle Aged
  • Neuroma / diagnostic imaging*
  • Neuroma, Acoustic / diagnostic imaging*
  • Peripheral Nervous System Neoplasms / diagnostic imaging*
  • Retrospective Studies
  • Spinal Nerves*
  • Tomography, Emission-Computed*

Substances

  • Fluorodeoxyglucose F18
  • Deoxyglucose