Multicenter evaluation of the fully automated Bactec MGIT 960 system for susceptibility testing of Mycobacterium tuberculosis to pyrazinamide: comparison with the radiometric Bactec 460TB system

J Microbiol Methods. 2003 Oct;55(1):331-3. doi: 10.1016/s0167-7012(03)00142-8.

Abstract

One hundred and fifty clinical isolates of Mycobacterium tuberculosis were tested for susceptibility to pyrazinamide using the fully automated Bactec MGIT 960 system and the radiometric Bactec 460TB system. The overall concordance rate between MGIT 960 and radiometric system was 100% and the mean turnaround times to report the susceptibility test results were almost identical (6.37 and 6.8 days, respectively).

Publication types

  • Comparative Study
  • Multicenter Study

MeSH terms

  • Antitubercular Agents / pharmacology*
  • Microbial Sensitivity Tests / methods*
  • Mycobacterium tuberculosis / drug effects*
  • Pyrazinamide / pharmacology*
  • Radiometry

Substances

  • Antitubercular Agents
  • Pyrazinamide