Presence of HCV RNA in serum of asymptomatic blood donors involved in post-transfusion hepatitis (PTH)

E Villa; M Melegari; I Ferretti; C Vecchi; P P Scaglioni; M De Palma; F Manenti

doi:10.1007/978-3-7091-5633-9_54

Presence of HCV RNA in serum of asymptomatic blood donors involved in post-transfusion hepatitis (PTH)

Arch Virol Suppl. 1992:4:247-8. doi: 10.1007/978-3-7091-5633-9_54.

Authors

E Villa¹, M Melegari, I Ferretti, C Vecchi, P P Scaglioni, M De Palma, F Manenti

Affiliation

¹ Chair of Gastroenterology, University of Modena, Italy.

PMID: 1450695
DOI: 10.1007/978-3-7091-5633-9_54

Abstract

To study the causes of residual posttransfusion hepatitis, serum from implicated donors was tested by PCR for the presence of HCV RNA. Of 20 anti HCV negative donors, 4 were HCV RNA positive and thus, infective. The results suggest that higher-level investigations are necessary for prospective donors who present blood enzyme abnormalities or other questionable characteristics.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Alanine Transaminase / blood
Blood Donors*
Hepatitis C / etiology*
Hepatitis C / prevention & control
Hepatitis C / transmission
Humans
Polymerase Chain Reaction
RNA, Viral / blood*
Transfusion Reaction*

Substances

RNA, Viral
Alanine Transaminase