Secoiridoid glycoside and alkaloid constituents of Hydrangea chinensis

J Nat Prod. 2003 Sep;66(9):1245-8. doi: 10.1021/np0302394.

Abstract

A new secoiridoid glycoside, hydrachoside A (1), along with 14 known compounds, was isolated from the leaves of Hydrangea chinensis. The absolute stereochemistry of the side chain attached to C-15 on the secoiridoid glycoside hydrangenoside E (2) was determined by NMR spectral analysis. The structures of compounds 1 and 2 were elucidated on the basis of spectral data. The previously reported structure, hydrachine A (3), was revised as its epimer, (-)-neodichroine (4), a new compound.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkaloids / chemistry
  • Alkaloids / isolation & purification*
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Hydrangea / chemistry*
  • Iridoids / chemistry
  • Iridoids / isolation & purification*
  • Medicine, Traditional
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Leaves / chemistry
  • Plants, Medicinal / chemistry*
  • Stereoisomerism

Substances

  • Alkaloids
  • Drugs, Chinese Herbal
  • Iridoids
  • hydrachine A
  • hydrachoside A
  • hydrangenoside E