Primary amenorrhea-galactorrhea with hyperprolactinemia and huge pituitary enlargement in juvenile primary hypothyroidism

L Chaieb; M Chadli-Chaieb; A Chaieb; A Zebidi; M Allegue

doi:10.1016/0028-2243(92)90264-y

Primary amenorrhea-galactorrhea with hyperprolactinemia and huge pituitary enlargement in juvenile primary hypothyroidism

Eur J Obstet Gynecol Reprod Biol. 1992 Sep 23;46(2-3):159-62. doi: 10.1016/0028-2243(92)90264-y.

Authors

L Chaieb¹, M Chadli-Chaieb, A Chaieb, A Zebidi, M Allegue

Affiliation

¹ Endocrine-Metabolic Service, Farhat Hached Hospital, Sousse, Tunisia.

PMID: 1451896
DOI: 10.1016/0028-2243(92)90264-y

Abstract

We report a girl with juvenile primary hypothyroidism revealed by growth retardation and a syndrome of primary amenorrhea-galactorrhea with hyperprolactinemia and suprasellar pituitary enlargement. Resolution of the pituitary enlargement and the amenorrhea-galactorrhea syndrome occurred after thyroid hormone replacement. No similar observation has been reported earlier in juvenile hypothyroidism.

Publication types

Case Reports

MeSH terms

Adult
Amenorrhea / etiology*
Female
Galactorrhea / etiology*
Growth Disorders / etiology*
Humans
Hyperprolactinemia / etiology*
Hypothyroidism / complications*
Hypothyroidism / pathology
Sella Turcica / pathology*
Syndrome