Synthesis of an asymmetrically substituted AZA crown ether as metal and amino acid binding site in DNA conjugates

Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1039-40. doi: 10.1081/NCN-120022730.

Abstract

Crown ether 4 as a receptor core for protonated primary amines such as amino acids has been synthesized and incorporated into oligodeoxynucleotides as dangling ends.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amides / chemistry
  • Amino Acids / chemistry
  • Aza Compounds / chemical synthesis*
  • Aza Compounds / chemistry
  • Binding Sites
  • Crown Ethers / chemical synthesis*
  • Crown Ethers / chemistry
  • DNA / chemistry*
  • Metals / chemistry
  • Oligodeoxyribonucleotides / chemical synthesis*
  • Oligodeoxyribonucleotides / chemistry
  • Phosphoric Acids / chemistry

Substances

  • Amides
  • Amino Acids
  • Aza Compounds
  • Crown Ethers
  • Metals
  • Oligodeoxyribonucleotides
  • Phosphoric Acids
  • DNA
  • phosphoramidic acid