Using data from an ongoing study of 178 single-mother, Black families, this study investigates the relations among family resources (mothers' employment, income from employment, and educational attainment), maternal depressive symptoms, neighborhood quality in the preschool years and over time, and child developmental outcomes (behavior problems, broad reading, calculation) in the early school years. Results indicate that behavior problems in school-age children were associated with behavior problems early on, the child's gender, the mother's depressive symptoms and, to some extent, her employment status. However, these findings were conditioned by the mother's educational attainment and her evaluation of neighborhood problems early on. Better broad reading scores were associated with higher maternal educational attainment, especially for school-age girls of employed mothers, whereas higher calculation scores were predicted by fewer school-age behavior problems and, in the presence of higher neighborhood problems in the preschool years, mothers' higher educational attainment.