Substructure search procedures for macromolecular structures

Acta Crystallogr D Biol Crystallogr. 2003 Nov;59(Pt 11):1966-73. doi: 10.1107/s0907444903018043. Epub 2003 Oct 23.

Abstract

This paper accompanies a lecture given at the 2003 CCP4 Study Weekend on experimental phasing. The first part is an overview of the fundamentals of Patterson methods and direct methods with the audience of the CCP4 Study Weekend in mind. In the second part, a new hybrid substructure search is outlined.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Crystallography, X-Ray / methods*
  • Fourier Analysis
  • Macromolecular Substances*
  • Proteins / chemistry

Substances

  • Macromolecular Substances
  • Proteins