Abstract
Nine novel oxylipin metabolites together with several known ones were isolated from the brown alga Eisenia bicyclis. Five (1-5) of them are ecklonialactone derivatives containing a chlorine or an iodine atom, and two (6 and 7) are cymathere type oxylipins with a lactone ring or a chlorine atom. The structures of these oxylipin metabolites were confirmed by NMR and mass spectroscopy and compared with spectral data in the literature. The postulated biosynthetic pathway of these metabolites is discussed.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Infective Agents / chemistry
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Anti-Infective Agents / isolation & purification*
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Anti-Infective Agents / pharmacology
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Bacillus subtilis / drug effects
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Cyclopentanes / chemistry
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Cyclopentanes / isolation & purification*
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Cyclopentanes / pharmacology
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Fatty Acids, Unsaturated / metabolism*
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Heterocyclic Compounds, 2-Ring / chemistry
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Heterocyclic Compounds, 2-Ring / isolation & purification*
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Heterocyclic Compounds, 2-Ring / pharmacology
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Japan
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Phaeophyceae / chemistry*
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Staphylococcus aureus / drug effects
Substances
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Anti-Infective Agents
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Cyclopentanes
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Fatty Acids, Unsaturated
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Heterocyclic Compounds, 2-Ring