Volumetric diffuse optical tomography of brain activity

Opt Lett. 2003 Nov 1;28(21):2061-3. doi: 10.1364/ol.28.002061.

Abstract

We present three-dimensional diffuse optical tomography of the hemodynamic response to somatosensory stimulation in a rat. These images show the feasibility of volumetrically imaging the functional response to brain activity with diffuse light. A combination of positional optode calibration and contrast-to-noise ratio weighting was found to improve imaging performance.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Algorithms
  • Animals
  • Brain / physiology*
  • Computer Simulation
  • Feasibility Studies
  • Forelimb / physiology
  • Image Processing, Computer-Assisted
  • Light
  • Models, Theoretical
  • Rats
  • Scattering, Radiation
  • Tomography, Optical Coherence*