LDA--a java-based linkage disequilibrium analyzer

Keyue Ding; Kaixin Zhou; Fuchu He; Yan Shen

doi:10.1093/bioinformatics/btg276

LDA--a java-based linkage disequilibrium analyzer

Bioinformatics. 2003 Nov 1;19(16):2147-8. doi: 10.1093/bioinformatics/btg276.

Authors

Keyue Ding¹, Kaixin Zhou, Fuchu He, Yan Shen

Affiliation

¹ Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (and Peking Union Medical College, National Laboratory of Medical Molecular Biology, Beijing, 100005, People's Republic of China.

PMID: 14594722
DOI: 10.1093/bioinformatics/btg276

Abstract

We describe an integrated java-based program that provides elaborate graphic and plain-text output of pairwise linkage disequilibrium (LD) analysis of single nucleotide polymorphisms genotypic data. It is most suitable for molecular geneticists, who are focusing on LD measures estimation, statistical significance test and extent prediction.

Availability: The software is available at: http://www.chgb.org.cn/lda/lda.htm.

Supplementary information: Detailed tutorials, LDA help system and examples are distributed within LDA software. For Macintosh OS X user, the Jre version 1.4 can be downloaded from http://connect.apple.com.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Algorithms*
Database Management Systems*
Gene Expression Profiling / methods*
Gene Frequency
Hypermedia*
Linkage Disequilibrium / genetics*
Polymorphism, Single Nucleotide / genetics*
Sequence Alignment / methods*
User-Computer Interface*