Abstract
Human metapneumovirus (hMPV) associated with clinical respiratory tract infection (RTI) in children was first isolated in The Netherlands. Of 120 Thai paediatric patients with RTI examined, 5 cases (4.2%) showed detectable hMPV based on N-gene-specific RT-PCR. All of them were negative for hRSV infection. Aligning the sequences with a reference strain revealed some nucleotide differences, which necessitates future investigation to evaluate clinical significance and genotype variation.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Base Sequence
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Child
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Child, Preschool
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Female
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Gene Amplification
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Humans
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Infant
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Male
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Metapneumovirus / classification
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Metapneumovirus / genetics
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Metapneumovirus / isolation & purification*
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Molecular Sequence Data
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Paramyxoviridae Infections / diagnosis
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Paramyxoviridae Infections / epidemiology*
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Paramyxoviridae Infections / virology
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Prevalence
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RNA, Viral / analysis
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Respiratory Tract Infections / diagnosis
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Respiratory Tract Infections / epidemiology*
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Respiratory Tract Infections / virology
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Reverse Transcriptase Polymerase Chain Reaction
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Seasons
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Sequence Alignment
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Thailand / epidemiology