Simplified serological diagnosis of endocarditis due to Coxiella burnetii and Bartonella

Clin Diagn Lab Immunol. 2003 Nov;10(6):1147-8. doi: 10.1128/cdli.10.6.1147-1148.2003.

Abstract

We tested a single-step serological assay against Coxiella burnetii and Bartonella species and found a sensitivity of 100%, and a positive predictive value of 98% for the diagnosis of blood culture-negative endocarditis (BCNE). This assay should be considered as a possible commercial test for the diagnosis of BCNE.

MeSH terms

  • Antibodies, Bacterial / blood
  • Bartonella / immunology*
  • Bartonella / isolation & purification
  • Case-Control Studies
  • Coxiella burnetii / immunology*
  • Coxiella burnetii / isolation & purification
  • Cross Reactions / immunology
  • Endocarditis / etiology
  • Endocarditis / microbiology*
  • Humans
  • Immunoglobulin G / blood
  • Predictive Value of Tests
  • Q Fever / diagnosis
  • Q Fever / microbiology
  • Sensitivity and Specificity
  • Serologic Tests / methods
  • Serologic Tests / standards

Substances

  • Antibodies, Bacterial
  • Immunoglobulin G