Disseminated cryptococcosis in a patient with pituitary Cushing's disease

Korean J Intern Med. 2003 Sep;18(3):199-201. doi: 10.3904/kjim.2003.18.3.199.

Abstract

Disseminated cryptococcosis mainly occurs in patients with cell-mediated immunity disorders. A case of disseminated cryptococcosis, in a patient with pituitary Cushing's disease, is reported. Cultures of blood, cerebrospinal fluid (CSF) and aspirates of a skin lesion all grew Cryptococcus neoformans. Despite antifungal treatment, with amphotericin-B, the patient died within 3 weeks.

Publication types

  • Case Reports

MeSH terms

  • Amphotericin B / therapeutic use
  • Antifungal Agents / therapeutic use
  • Brain / diagnostic imaging
  • Brain / microbiology
  • Brain / pathology
  • Cryptococcosis / complications*
  • Cryptococcosis / diagnostic imaging
  • Cryptococcosis / drug therapy
  • Cushing Syndrome / complications*
  • Cushing Syndrome / microbiology
  • Fatal Outcome
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Middle Aged
  • Pituitary Diseases / complications*
  • Pituitary Diseases / diagnostic imaging
  • Pituitary Diseases / microbiology
  • Radiography

Substances

  • Antifungal Agents
  • Amphotericin B