Bacillary haemoglobinuria diagnosis by the peroxidase-antiperoxidase (PAP) technique

Zentralbl Veterinarmed B. 1992 Oct;39(8):595-8. doi: 10.1111/j.1439-0450.1992.tb01210.x.

Abstract

A peroxidase-antiperoxidase (PAP) technique was used to diagnose bacillary haemoglobinuria in formalin-fixed, paraffin-embedded liver tissues of cattle. The PAP method revealed Clostridium haemolyticum in the zone of liver necrosis characteristic of the disease and also in culture smears of this microorganism, but C. novyi type B, C. chauvoei, C. septicum and C. perfringens types B and C remained unstained by the PAP reaction. The PAP technique performed provides a specific, simple and rapid method to diagnose bacillary haemoglobinuria.

MeSH terms

  • Animals
  • Cattle
  • Cattle Diseases / diagnosis*
  • Clostridium / isolation & purification*
  • Clostridium Infections / diagnosis
  • Clostridium Infections / veterinary*
  • Hemoglobinuria / diagnosis
  • Hemoglobinuria / veterinary*
  • Immunoenzyme Techniques / veterinary*
  • Liver / microbiology