Abstract
The spread of orf513-bearing class 1 integrons is associated with bla(CTX-M-2) in gram-negative clinical isolates in Argentina, with In35 being the most frequently found integron (74%). Among 65 isolates without bla(CTX-M-2), only one harbored a novel orf513-bearing class 1 integron with the dfrA3b gene. The finding of orf513 not associated with class 1 integrons in two gram-positive strains indicates the widespread occurrence of this putative site-specific recombinase.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Argentina / epidemiology
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Bacterial Infections / epidemiology
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Bacterial Infections / microbiology
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Base Sequence
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DNA Primers
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Drug Resistance, Multiple, Bacterial / genetics*
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Genes, Bacterial / genetics*
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Humans
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Integrons / genetics*
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Microbial Sensitivity Tests
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Molecular Epidemiology
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Molecular Sequence Data
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Reverse Transcriptase Polymerase Chain Reaction
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beta-Lactamases / genetics*
Substances
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DNA Primers
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beta-lactamase CTX-2
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beta-Lactamases