Cutaneous lymphoplasmacytoid lymphoma (immunocytoma) with Waldenström's macroglobulinemia mimicking rosacea

Jill H Colvin; Cindy L Lamerson; Hernani Cualing; Diya F Mutasim

doi:10.1016/s0190-9622(03)00475-4

Cutaneous lymphoplasmacytoid lymphoma (immunocytoma) with Waldenström's macroglobulinemia mimicking rosacea

J Am Acad Dermatol. 2003 Dec;49(6):1159-62. doi: 10.1016/s0190-9622(03)00475-4.

Authors

Jill H Colvin¹, Cindy L Lamerson, Hernani Cualing, Diya F Mutasim

Affiliation

¹ Department of Dermatology, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0592, USA.

PMID: 14639408
DOI: 10.1016/s0190-9622(03)00475-4

Abstract

A 50-year-old woman presented with a 2-year history of facial lesions that were resistant to rosacea therapy. Evaluation of histology, immunohistochemistry, gene rearrangement study, bone-marrow biopsy specimen, and systemic workup revealed the findings of lymphoplasmacytoid lymphoma (immunocytoma) in both the skin lesions and bone marrow, and IgM kappa paraprotein. Lesions cleared after chemotherapy.

Publication types

Case Reports

MeSH terms

Bone Marrow Cells
Diagnosis, Differential
Female
Gene Rearrangement
Humans
Immunoglobulin M / analysis
Immunoglobulin kappa-Chains / analysis
Immunohistochemistry
Leukemia, Lymphocytic, Chronic, B-Cell
Lymphoma, B-Cell / pathology*
Middle Aged
Paraproteins / analysis
Rosacea / pathology*
Skin Neoplasms / pathology*
Waldenstrom Macroglobulinemia / pathology*

Substances

Immunoglobulin M
Immunoglobulin kappa-Chains
Paraproteins