Ethical problems of evaluating a new treatment for melioidosis

BMJ. 2003 Nov 29;327(7426):1280-2. doi: 10.1136/bmj.327.7426.1280.

Abstract

When mortality from melioidosis fell sharply after multiple changes in management at an Australian hospital, doctors wanted to identify whether a new drug was responsible. But designing a trial that was ethically acceptable proved impossible

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Ethics, Medical
  • Granulocyte Colony-Stimulating Factor / therapeutic use*
  • Humans
  • Melioidosis / drug therapy*
  • Randomized Controlled Trials as Topic / ethics*

Substances

  • Granulocyte Colony-Stimulating Factor